Organizing the HIV vaccine development effort
نویسندگان
چکیده
منابع مشابه
HIV Vaccine Development.
Several interesting new vaccine-related studies were presented at the 16th Conference on Retroviruses and Opportunistic Infections this year. Transmitted viruses appear to be derived from cell-free virus rather than cell-associated virus, at least in men who have sex with men. Follow-up studies from the Step (HIV Vaccine Trials Network 502) trial indicated that if individuals mounted certain va...
متن کاملHIV vaccine development.
For the past two decades, scientists have aggressively pursued the development of a vaccine against human immunodeficiency virus (HIV). The magnitude of this effort is unprecedented in the history of infectious diseases. However, difficulties in finding promising candidate vaccines have limited the number of clinical efficacy trials. The macaque model is well suited for the evaluation of potent...
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New information on the crystal structures of the HIV and the simian immunodeficiency virus (SIV) envelopes represented one of the scientific highlights of the 12th Annual Conference on Retroviruses and Opportunistic Infections. Numerous presentations also underscored the increasing recognition of the central role of gut-associated lymphoid tissue in AIDS pathogenesis and helped reveal a better ...
متن کاملProgress in HIV vaccine development.
Recent advances in HIV vaccine development include initiation of the first efficacy trials and substantial expansion of the preclinical pipeline. Several preclinical candidate vaccines have induced strong cellular immune responses and provided impressive protection against AIDS in non-human primate models; however, candidates that induce broadly neutralizing antibodies remain elusive.
متن کاملAfrican AIDS Vaccine Programme for a Coordinated and Collaborative Vaccine Development Effort on the Continent
N early 30 years after the first cases of AIDS were reported [1] and HIV identified as the causative agent, Africa today bears a disproportionate burden of the disease. Sub-Saharan Africa has just over 10% of the world's population but is home to more than 65% of the 33 million people in the world estimated to be living with HIV/AIDS. The annual rate of new infections continues to rise, with an...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2013
ISSN: 1746-630X
DOI: 10.1097/coh.0b013e328363f5b6